Ozempic users may be making a major weight-loss mistake, new study suggests

Among those taking GLP-1 medications for weight loss, workout rates are decreasing, according to caller research.

The study, group to beryllium presented astatine ENDO 2026 (the Endocrine Society's yearly meeting) successful Chicago this week, recovered that adults pinch obesity who mislaid weight pinch a GLP-1, specified arsenic Ozempic aliases Wegovy, "significantly reduced" their beingness activity.

In an Endocrine Society property release, study lead Sajana Maharjan, MD, of HSHS St. John's Hospital successful Springfield, Illinois, noted that GLP-1 narcotics for illustration semaglutide, liraglutide, dulaglutide and tirzepatide trim some fat and thin musculus mass.

'WILD WEST' PEPTIDE CRAZE SURGES BEYOND GLP-1S AS FDA FACES PRESSURE TO EASE ACCESS

This intends beingness activity is "essential for preserving spot and long-term health," she said.

The study, reportedly nan first of its kind, considered information from a National Institutes of Health investigation programme that linked subordinate records pinch fittingness locator activity.

Researchers analyzed information from 753 group pinch obesity who initiated a GLP-1 medication. The cohort was mostly female, astatine a mean property of 52.7 years.

Among participants, nan mean number of steps decreased from 5,047 to 4,487 per day. (iStock)

Comparing activity successful participants earlier and aft opening treatment, nan mean number of steps decreased from 5,047 to 4,487 per day. Moderate-to-vigorous beingness activity fell from 28 to 22 minutes per day, nan study found.

The largest declines were observed successful men and successful those pinch associated aliases musculus pain. Other factors for illustration age, bosom nonaccomplishment aliases prior stroke did not alteration results.

OZEMPIC ‘MICRODOSING’ IS THE NEW WEIGHT-LOSS TREND: SHOULD YOU TRY IT?

Although galore group mightiness presume that losing weight pinch these medications would lead to accrued physical activity, nan study recovered nary grounds that it did, according to Maharjan.

"The findings successful our study reenforce that workout cannot beryllium optional for group taking these medications," he said. "People request targeted interventions that promote beingness activity alongside medicine for obesity."

FITNESS EXPERT REVEALS SIMPLE RULE TO GET IN SHAPE WITHOUT DREADING THE GYM: 'JUST MOVE'

The study was retrospective and observational, meaning it could only show an association, not a nonstop cause. The participants were besides mostly middle-aged women, which could limit nan scope of who is astir impacted, nan researchers noted.

Other factors that were not measured see workout habits earlier starting treatment, information levels and guidance from a physician.

Although galore group mightiness presume that losing weight pinch these medications would lead to accrued beingness activity, nan study recovered nary grounds that it did, according to nan researcher. (iStock)

Dr. Peter Balazs MD, a hormone and weight-loss master practicing successful New York and New Jersey, echoed successful an question and reply pinch Fox News Digital that weight nonaccomplishment does not automatically lead to accrued mobility aliases greater information to exercise.

"In fact, being successful a calorie shortage tin origin nan assemblage to conserve energy, resulting successful a little metabolic rate," he said.

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

"Additionally, broadside effects of weight-loss medications, specified arsenic nausea, fatigue aliases gastrointestinal discomfort, whitethorn further trim a person's expertise aliases desire to beryllium physically active," nan master added.

For GLP-1 users, Balazs stressed that workout "is not optional." Patients must incorporated resistance training and regular daily movement, for illustration walking, into their regular to "preserve thin musculus mass, support metabolic wellness and support semipermanent weight management," he advised.

Exercise supports bony and associated wellness and enhances cardiovascular fitness, nan interrogator said. (iStock)

"Exercise plays a captious domiciled during weight loss," Balazs said. "Without capable beingness activity, a important information of weight nonaccomplishment whitethorn travel from musculus alternatively than fat."

The master noted that location is not a one-size-fits-all approach, arsenic nan timing, strength and type of workout should beryllium individualized based connected a person’s fittingness level, wellness position and assemblage composition.

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

"This is peculiarly important for patients pinch a precocious BMI who whitethorn person mobility limitations aliases little baseline fittingness levels," Balazs said. "It's important to see wounded risk, semipermanent adherence and nan imaginable for early burnout."

Contrasting views

Board-certified internist and longevity master Dr. Amanda Kahn said she disagrees pinch this study’s conclusions, arsenic they do not bespeak what she is seeing successful her ain clinical practice.

"Weight nonaccomplishment often serves arsenic nan impetus that motivates patients to go much physically progressive and much engaged successful their wide health," nan New York-based master told Fox News Digital.

Successful curen requires regular follow-up, monitoring of macromolecule intake, monthly weight checks, quarterly assemblage creation scans and regular laboratory testing, an master advised. (iStock)

"The occurrence of GLP-1 therapy is straight tied to nan expertise of nan provider," she went on. "When these medications are prescribed thoughtfully – pinch attraction to nutrition, guidance training, assemblage creation and laboratory monitoring – they tin thief patients suffer weight while becoming healthier, stronger and much motivated to exercise."

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Kahn, a peptide prescriber, does not urge simply prescribing a GLP-1 medicine and allowing nan diligent to "self-manage."

"In my practice, if a diligent is incapable to exercise, is not gathering protein goals aliases shows concerning musculus nonaccomplishment connected assemblage creation analysis, I will often clasp aliases set nan medicine – because preserving strength, usability and metabolic wellness is conscionable arsenic important arsenic weight loss," she said.

CLICK HERE FOR MORE HEALTH STORIES

If a GLP-1 diligent becomes excessively fatigued to exercise, develops nutritional deficiencies aliases loses excessive musculus mass, Kahn warned that this reflects a "monitoring problem" alternatively than a medicine problem, arsenic these medications "require adjacent objective oversight."